Circuitry and Function of the Dorsal Cochlear Nucleus
نویسندگان
چکیده
منابع مشابه
A Simulation-Based Study of Dorsal Cochlear Nucleus Pyramidal Cell Firing Patterns
A two-variable integrate and fire model is presented to study the role of transient outward potassium currents in producing temporal aspects of dorsal cochlear nucleus (DCN) pyramidal cells with different profiles namely the chopper, the pauser and the buildup. This conductance based model is a reduced version of KM-LIF model (Meng & Rinzel, 2010) which captures qualitative firing features of a...
متن کاملDorsal cochlear nucleus hyperactivity and tinnitus: are they related?
PURPOSE Eight lines of evidence implicating the dorsal cochlear nucleus (DCN) as a tinnitus contributing site are reviewed. We now expand the presentation of this model, elaborate on its essential details, and provide answers to commonly asked questions regarding its validity. CONCLUSIONS Over the past decade, numerous studies have converged to support the hypothesis that the DCN may be an im...
متن کاملAuditory-somatosensory bimodal stimulation desynchronizes brain circuitry to reduce tinnitus in guinea pigs and humans.
The dorsal cochlear nucleus is the first site of multisensory convergence in mammalian auditory pathways. Principal output neurons, the fusiform cells, integrate auditory nerve inputs from the cochlea with somatosensory inputs from the head and neck. In previous work, we developed a guinea pig model of tinnitus induced by noise exposure and showed that the fusiform cells in these animals exhibi...
متن کاملActivation of the central nervous system induced by micro-magnetic stimulation
Electrical and transcranial magnetic stimulations have proven to be therapeutically beneficial for patients suffering from neurological disorders. Moreover, these stimulation technologies have provided invaluable tools for investigating nervous system functions. Despite this success, these technologies have technical and practical limitations impeding the maximization of their full clinical and...
متن کاملSpectral edge sensitivity in neural circuits of the dorsal cochlear nucleus.
One possible function of the dorsal cochlear nucleus (DCN) is discrimination of head-related transfer functions (HRTFs), spectral cues used for vertical sound localization. Recent psychophysical and physiological studies suggest that steep, rising spectral edges may be the features used to identify HRTFs. Here we showed, using notch noise and noise band stimuli presented over a range of frequen...
متن کامل